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Arizona Cardinals vs. Indianapolis Colts Odds, Predictions, Expert Picks 12/25/2021

Author-Avatar
Author:
Stefan Scekic
Last Updated:
January 12, 2022
Approved
Author
This author was thoroughly tested and approved by the experts at BettingBilly.com before joining the editorial board to ensure a high content quality.
Author Bio:
 
Stefan is one of the Tipsters at our BettingBilly Team. You can follow his success in our free section as well as in Billy's List. Most of his time he's watching and analyzing football and basketball to serve you with the very best picks you can get.
Stefan is one of the Tipsters at our BettingBilly Team. You can follow his success in our free section as well as in Billy's List. Most of his time he's watching and analyzing football and basketball to serve you with the very best picks you can get.
Arizona Cardinals vs. Indianapolis Colts Odds, Predictions, Expert Picks 12/25/2021 Thumbnail
Arizona Cardinals
vs.
16-22
Indianapolis Colts
Took place: 25/12/2021 8:15 pm in Glendale, Arizona
Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed

Arizona Cardinals and Indianapolis Colts will face each other on Saturday evening in the NFL 2021 Week 16 action. The home side wants to break its losing streak and remain on the pole position in their division. The visitors still chase the playoffs spot, and they look forward to booking another good result.

Arizona was dominant until the previous few weeks, when their form declined. The hosts are on the right track to entering the post-season, and they want to stabilize their game. On the other hand, Indianapolis improved its performances lately and got back into the playoffs battle. The away side intends to continue in the same fashion and remain in the division top-spot race.

Arizona Cardinals vs. Indianapolis Colts Odds, Predictions, Expert Picks 12/25/2021 Thumbnail
Our expert picks
Pick #1
Indianapolis Colts +1
Best odds
-110
Units: 6/10
Additional Pick
Over 49
Best odds
-110
Units: 5/10
Additional Pick
Colts Over 24.5
Best odds
-110
Units: 4/10
Your Expert:
+105%
Stefan Scekic

Arizona Cardinals – Can they get back to the winning track?

The Cardinals enjoyed a strong start into the regular season, and they lost just once in the first nine rounds. However, the home side suffered three defeats in the previous five games, losing the last two as well. Nevertheless, they still top the NFC West with a 10-4 record, the same as Los Angeles Rams. Arizona goes to this game after a surprising defeat away to the worst team in the NFL – Detroit Lions – who celebrated an easy 30-12 victory. The Cardinals gained 398 yards in the offense but couldn’t convert them into points.

Kyler Murray has gone 3,039 yards through the air so far, with 20 TDs and ten picks, while he was sacked 25 times. James Conner has gained 700 rushing yards and 14 scores, while Chase Edmonds and Kyler Murray have combined for 753 rushing yards and six touchdowns. Christian Kirk and A.J. Green dominate the receiving corps with 700+ receiving yards each, followed by a combined eight touchdown receptions. On the other hand, Jordan Hicks has a team-high 105 total tackles, while Markus Golden has logged 11 sacks.

Expected Line-Up (Offense): James Conner, Antoine Wesley, A.J. Green, Christian Kirk, Zach Ertz, D.J. Humphries, Justin Pugh, Max Garcia, Josh Jones, Kelvin Beachum

Expected Line-Up (Defense): Michael Dogbe, Corey Peters, Zach Allen, Chandler Jones, Jordan Hicks, Isaiah Simmons, Markus Golden, Byron Murphy Jr., Jalen Thompson, Budda Baker, Marco Wilson

Quarter Back: Kyler Murray

Kicker: Matt Prater

Arizona Cardinals vs. Indianapolis Colts Odds, Predictions, Expert Picks 12/25/2021 Thumbnail
Bet now at the betting site 
with best odds
Best odds
-110

Indianapolis Colts – Will they secure the playoffs spot?

The Colts are running hot lately, celebrating five times on the previous six occasions. That excellent streak launched them to the 2nd spot in the AFC South, being just one victory behind top-placed Tennessee. Indianapolis booked a massive win against the Patriots last weekend, which was their second straight. Despite producing only 275 yards in the offense, opposed to the Pats’ 365 yards, they completely outrushed the opponents.

Indianapolis’ starting quarterback Carson Wentz has passed for 3,005 yards, with 23 touchdowns and six interceptions, while the opponent defenders sacked him 23 times. Jonathan Taylor leads the Colts’ ground game with 1,518 yards and 17 scores, while Nyheim Hines, Carson Wentz, and Marlon Mack have combined for 546 rushing yards and three TDs. Michael Pittman Jr. leads the receiving department with 889 yards and five touchdown receptions, while Zach Pascal and Jonathan Taylor generated 300+ receiving yards each. Bobby Okereke dominates the defensive corps with 110 total tackles, while DeForest Buckner has 6.5 sacks.

Expected Line-Up (Offense): Jonathan Taylor, Michael Pittman Jr., T.Y. Hilton, Zach Pascal, Jack Doyle, Eric Fisher, Quenton Nelson, Danny Pinter, Mark Glowinski, Braden Smith

Expected Line-Up (Defense): Kwity Paye, DeForest Buckner, Grover Stewart, Al-Quadin Muhammad, Darius Leonard, Bobby Okereke, Zaire Franklin, Rock Ya-Sin, Khari Willis, George Odum, Xavier Rhodes

Quarter Back: Carson Wentz

Kicker: Michael Badgley

Arizona Cardinals vs. Indianapolis Colts Odds, Predictions, Expert Picks 12/25/2021 Thumbnail
Our expert picks
Pick #1
Indianapolis Colts +1
Best odds
-110
Units: 6/10
Additional Pick
Over 49
Best odds
-110
Units: 5/10
Additional Pick
Colts Over 24.5
Best odds
-110
Units: 4/10
Your Expert:
+105%
Stefan Scekic

Expert Pick #1 – Indianapolis Colts +1 @-110

Although Arizona has been excellent this season, I’m going to back the visitors as my first pick here. The Cardinals will have selection troubles, and they don’t need to force questionable players. They probably already look forward to the post-season while the Colts chase a valuable victory. Give me Indianapolis ATS.

Expert Pick #2 – Over 49 @-110

Both teams have been involved in high-scoring games pretty often this season. The Over cashed four times in the Cardinals’ last five games, while five of the Colts’ previous six games against the NFC opponent went over the margin. I’ll take the Over as my second bet.

Expert Pick #3 – Colts Over 24.5 @-110

Consequently, the third pick arises as a good alternative with the same odds. Indianapolis produced more than 24 points on the previous four occasions, and they want to keep their good scoring streak going.

99/100
Colts to fight for the post-season spot
It’s going to be a close matchup that can go either way. I’m leaning towards the visitors, who won’t have selection issues like their rivals. Besides, this game is more important for the Colts, and they’ll try to get back home with a win. The fans should see an interesting match, and the away side could score at least 25 points.
Arizona Cardinals vs. Indianapolis Colts Odds, Predictions, Expert Picks 12/25/2021 Thumbnail
Our expert picks
Pick #1
Indianapolis Colts +1
Best odds
-110
Units: 6/10
Additional Pick
Over 49
Best odds
-110
Units: 5/10
Additional Pick
Colts Over 24.5
Best odds
-110
Units: 4/10
Your Expert:
+105%
Stefan Scekic

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