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Buffalo Bills vs. Indianapolis Colts Odds, Predictions, Expert Picks 11/21/2021

Author-Avatar
Author:
Stefan Scekic
Last Updated:
December 1, 2021
Approved
Author
This author was thoroughly tested and approved by the experts at BettingBilly.com before joining the editorial board to ensure a high content quality.
Author Bio:
 
Stefan is one of the Tipsters at our BettingBilly Team. You can follow his success in our free section as well as in Billy's List. Most of his time he's watching and analyzing football and basketball to serve you with the very best picks you can get.
Stefan is one of the Tipsters at our BettingBilly Team. You can follow his success in our free section as well as in Billy's List. Most of his time he's watching and analyzing football and basketball to serve you with the very best picks you can get.
Buffalo Bills vs. Indianapolis Colts Odds, Predictions, Expert Picks 11/21/2021 Thumbnail
Buffalo Bills
vs.
15-41
Indianapolis Colts
Took place: 21/11/2021 1:00 pm in Orchard Park, New York
Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed

Buffalo Bills will host Indianapolis Colts in the NFL Week 11 action on Sunday afternoon. The hosts have played hot and cold recently, and they look forward to stabilizing their form. The away side has improved its performances lately, and they want to continue in the same fashion.

Buffalo is in a good position to secure the playoffs spot, but they need to be more consistent as the regular season nears the end. The hosts will search for another victory that should keep them at the top of the division. On the other hand, the visitors started playing much better after a slow start to the campaign. Indianapolis hopes to challenge for the post-season spot, and they search for another victory.

Buffalo Bills vs. Indianapolis Colts Odds, Predictions, Expert Picks 11/21/2021 Thumbnail
Our expert picks
Pick #1
Indianapolis Colts +7
Best odds
-105
Units: 6/10
Additional Pick
Over 50
Best odds
-110
Units: 5/10
Additional Pick
Bills & Over 44.5
Best odds
+100
Units: 3/10
Your Expert:
+99%
Stefan Scekic

Buffalo Bills – Can they be more consistent?

The Bills have been pretty inconsistent lately, but they go to this match after beating the Jets on the road last weekend. They improved to a 6-3 record, which keeps them on the top of the AFC East, ahead of New England Patriots. Buffalo was excellent in the offense, gaining 489 yards and scoring 45 points. Josh Allen led the Bills to a victory by throwing for 366 yards on 21-28, with a pair of scores and one interception. Devin Singletary gained 43 yards on seven carries for a TD, while Stefon Diggs and Gabriel Davis combined for 267 receiving yards.

Buffalo’s starting QB Josh Allen has passed for 2,602 yards with 19 touchdowns and six interceptions. He has completed 66.3% of his passes, while the opponent defenders sacked him 14 times. Allen and Devin Singletary have combined for 720 rushing yards and five TDs, while Zach Moss has 260 yards in the ground game. Stefon Diggs is the leading receiver with 750 yards and four scores, while Emmanuel Sanders generated 505 receiving yards. On the other hand, Tremaine Edmunds has led the Bills defense with 55 total tackles, while Greg Rousseau and Mario Addison logged three sacks each.

Expected Line-Up (Offense): Zack Moss, Stefon Diggs, Emmanuel Sanders, Cole Beasley, Dawson Knox, Reggie Gilliam, Dion Dawkins, Ike Boettger, Mitch Morse, Daryl Williams, Spencer Brown

Expected Line-Up (Defense): Greg Rousseau, Ed Oliver, Harrison Phillips, Jerry Hughes, Matt Milano, Tyrel Dodson, A.J. Klein, Tre’Davious White, Jordan Poyer, Micah Hyde, Levi Wallace

Quarter Back: Josh Allen

Kicker: Tyler Bass

Buffalo Bills vs. Indianapolis Colts Odds, Predictions, Expert Picks 11/21/2021 Thumbnail
Bet now at the betting site 
with best odds
Best odds
-105

Indianapolis Colts – Will they keep the high level of performance?

The Colts had a poor start to the season, but they managed to raise the level of their performances. Indianapolis celebrated four times on the previous five occasions and climbed to 2nd place in the AFC South, having a 5-5 record. The visitors go to this match after two straight home wins, hoping to continue the run. They were better than the Jaguars last time, celebrating a 23-17 victory. Carson Wentz passed for 180 yards on 22-34 but failed to find the end zone. Nevertheless, Jonathan Taylor was excellent in the ground game, rushing for 116 yards on 21 carries and producing a touchdown.

Carson Wentz hasn’t been impressive this season and has thrown for 2,378 yards with a 63.5 pass completion percentage, 17 TDs, and three interceptions. Jonathan Taylor has been dominant in the rushing department with 937 yards and nine scores, while Nyheim Hines produced 203 rushing yards and a pair of scores. Michael Pittman Jr. has been the leading receiver with 729 yards and five touchdowns, while Zach Pascal and Jonathan Taylor have combined for 631 receiving yards. Defensively, Bobby Okereke has a team-high 86 total tackles, while DeForest Buckner sacked the opponent quarterbacks 4.5 times.

Expected Line-Up (Offense): Jonathan Taylor, Michael Pittman Jr., T.Y. Hilton, Zach Pascal, Jack Doyle, Eric Fisher, Quenton Nelson, Ryan Kelly, Mark Glowinski, Braden Smith

Expected Line-Up (Defense): Kwity Paye, DeForest Buckner, Grover Stewart, Al-Quadin Muhammad, Darius Leonard, Bobby Okereke, Zaire Franklin, Rock Ya-Sin, George Odum, Andrew Sendejo, T.J. Carrie

Quarter Back: Carson Wentz

Kicker: Michael Badgley

Buffalo Bills vs. Indianapolis Colts Odds, Predictions, Expert Picks 11/21/2021 Thumbnail
Our expert picks
Pick #1
Indianapolis Colts +7
Best odds
-105
Units: 6/10
Additional Pick
Over 50
Best odds
-110
Units: 5/10
Additional Pick
Bills & Over 44.5
Best odds
+100
Units: 3/10
Your Expert:
+99%
Stefan Scekic

Expert Pick #1 – Indianapolis Colts +7 @-105

It is going to be an interesting matchup, as both teams go to this clash after celebrating victories. The Bills want to keep the top spot, while the Colts search for a chance to stay in the playoffs race. Indianapolis covered the number eight times on the previous ten outings, and they could continue in the same fashion. I’ll take the Colts ATS as my first pick.

Expert Pick #2 – Over 50 @-110

Both teams have been pretty productive in the offense this season, and I expect another high-scoring game. Jonathan Taylor is the NFL’s best rusher, while the Bills had an excellent offensive display last time. Therefore, I’ll go for the Over as the second bet.

Expert Pick #3 – Bills & Over 44.5 @+100

Although the Colts are not without a chance in this clash, I still believe the hosts will see off their opponents. Buffalo to win ML in the game with at least 45 points seems to be a solid pick for the plus money odds, and I’m going to back it.

97/100
The Bills to win a close matchup
Although they haven’t been consistent lately, I expect Buffalo to win this match and keep the top spot in the AFC East. On the other hand, I’m not convinced they can cover the number, but in any case, the crowd should enjoy an entertaining clash with at least 50 points.
Buffalo Bills vs. Indianapolis Colts Odds, Predictions, Expert Picks 11/21/2021 Thumbnail
Our expert picks
Pick #1
Indianapolis Colts +7
Best odds
-105
Units: 6/10
Additional Pick
Over 50
Best odds
-110
Units: 5/10
Additional Pick
Bills & Over 44.5
Best odds
+100
Units: 3/10
Your Expert:
+99%
Stefan Scekic

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