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Philadelphia Eagles vs. San Francisco 49ers Odds, Predictions, Expert Picks 09/19/2021

Author-Avatar
Author:
Stefan Scekic
Last Updated:
October 6, 2021
Approved
Author
This author was thoroughly tested and approved by the experts at BettingBilly.com before joining the editorial board to ensure a high content quality.
Author Bio:
 
Stefan is one of the Tipsters at our BettingBilly Team. You can follow his success in our free section as well as in Billy's List. Most of his time he's watching and analyzing football and basketball to serve you with the very best picks you can get.
Stefan is one of the Tipsters at our BettingBilly Team. You can follow his success in our free section as well as in Billy's List. Most of his time he's watching and analyzing football and basketball to serve you with the very best picks you can get.
Philadelphia Eagles vs. San Francisco 49ers Odds, Predictions, Expert Picks 09/19/2021 Thumbnail
Philadelphia Eagles
vs.
11-17
San Francisco 49ers
Took place: 19/09/2021 1:00 pm in Philadelphia, Pennsylvania
Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed   Closed

Philadelphia Eagles and San Francisco 49ers will face each other in the NFL 2021 season, Week 2. The hosts were very confident a week ago when they got back home with a win from Atlanta. The away side was also successful in the season opener, as they beat Detroit Lions on the road.

Philadelphia didn’t shine during the preseason, as they managed to pull out just one draw. They tied two defeats against the Steelers and the Patriots, while the victory against the Jets slipped away from their hands in the last moments of the game. On the other hand, the 49ers opened the preseason by losing to the Chiefs, but they bounced back with two wins. San Francisco celebrated against the Chargers while they were confident in the match versus the Raiders.

Philadelphia Eagles vs. San Francisco 49ers Odds, Predictions, Expert Picks 09/19/2021 Thumbnail
Our expert picks
Pick #1
Philadelphia Eagles +3.5
Best odds
-125
Units: 6/10
Additional Pick
Over 49
Best odds
-110
Units: 5/10
Additional Pick
The Eagles Over 21.5
Best odds
-140
Units: 6/10
Your Expert:
+94%
Stefan Scekic

Philadelphia Eagles – Can they improve in this season?

The Eagles’ slump was so quick that they went through the road from the Super Bowl champions to one of the worst teams in the league in just three years. Last season, the home side had a disappointing 4-12 score and finished at the NFC East basement. Carson Wentz’s era is over, and Philadelphia sets all hopes on the last year’s rookie Jalen Hurts at the quarterback. The Eagles will try to stabilize this season, as many experienced players left the team. On the other hand, they expect a big contribution from DeVonta Smith, the new receiver.

Philadelphia impressed in the opening match of the season, beating the Falcons 32-6. They controlled the entire game and Hurts passed for 264 yards in 27-35 and with three touchdowns. DeVonta Smith was the leading player in the receiving corps with six receptions and a score in a total of 71 yards. Sanders rushed for 74 yards on 15 carries, while Philadelphia gained a total of 434 yards in offense. The Eagles were excellent in defense as well, allowing only 260 yards to the Falcons. Eric Wilson and Avonte Maddox led Philadelphia’s defense with nine tackles each.

Expected Line-Up (Offense): Miles Sanders, DeVonta Smith, Jalen Reagor, Quez Watkins, Dallas Goedert, Jordan Mailata, Isaac Seumalo, Jason Kelce, Nate Herbig, Lane Johnson

Expected Line-Up (Defense): Brandon Graham, Javon Hargrave, Fletcher Cox, Derek Barnett, Alex Singleton, Eric Wilson, Genard Avery, Darius Slay, K’Von Wallace, Anthony Harris, Steven Nelson

Quarter Back: Jalen Hurts

Kicker: Jake Elliott

Philadelphia Eagles vs. San Francisco 49ers Odds, Predictions, Expert Picks 09/19/2021 Thumbnail
Bet now at the betting site 
with best odds
Best odds
-125

San Francisco 49ers – Can they shine this season?

The 49ers had many injury troubles last season, which resulted in a disappointing 6-10 record. However, they should have overcome these issues, and the visitors hope for a more successful campaign. Jimmy Garoppolo was out during most of the 2020 season, as well as George Kittle. Nick Bosa is also back on the roster, and he should strengthen the defense significantly. The 49ers signed a talented Trey Lance as a backup quarterback, but he could get a decent amount of playing time.

Jimmy G put up 314 yards on 17-25 and a TD in the game versus the Lions, while Eli Mitchell rushed for 104 yards on 19 carries to score. Deebo Samuel had nine catches and 189 receiving yards. On the other hand, Fred Warner led the 49ers’ defense with 11 tackles.

Expected Line-Up (Offense): Elijah Mitchell, Deebo Samuel, Brandon Aiyuk, Trent Sherfield, George Kittle, Kyle Juszczyk, Trent Williams, Laken Tomlinson, Alex Mack, Daniel Brunskill, Mike McGlinchey

Expected Line-Up (Defense): Kentavius Street, D.J. Jones, Nick Bosa, Fred Warner, Azeez Al-Shaair, Demetrius Flannigan-Fowles, Ambry Thomas, Jaquiski Tartt, Jimmie Ward, Deommodore Lenoir

Quarter Back: Jimmy Garoppolo

Kicker: Robbie Gould

Philadelphia Eagles vs. San Francisco 49ers Odds, Predictions, Expert Picks 09/19/2021 Thumbnail
Our expert picks
Pick #1
Philadelphia Eagles +3.5
Best odds
-125
Units: 6/10
Additional Pick
Over 49
Best odds
-110
Units: 5/10
Additional Pick
The Eagles Over 21.5
Best odds
-140
Units: 6/10
Your Expert:
+94%
Stefan Scekic

Expert Pick #1 – Philadelphia Eagles +3.5 @-125

Although the San Francisco attack is very powerful, the Eagles put an excellent defensive display against the Falcons. On the other hand, Philadelphia improved its offense with Hurts as a quarterback. The eagles covered the number five times on the previous six occasions at home. Therefore, I’ll go with Philadelphia to beat the spread as the major pick.

Expert Pick #2 – Over 49 @-110

I anticipate an entertaining clash in which we might see a high number of points. Both sides are doing well in offense, and they might keep up where they left off. As the first alternative bet, I’ll take the Over, as the margin is not too high.

Expert Pick #3 – The Eagles Over 21.5 @-140

As a consequence of the above two picks, I will go with Philadelphia to score more than 21.5 points. The odds are pretty decent, and I believe their offense is capable of beating this margin.

97/100
The Eagles for another good display
I expect to see a competitive game, as both sides will set their sights on a productive offense. Philadelphia could also add a solid defense that could lead them to cover the spread. We could see an efficient game, and the Eagles could contribute a lot to that outcome.
Philadelphia Eagles vs. San Francisco 49ers Odds, Predictions, Expert Picks 09/19/2021 Thumbnail
Our expert picks
Pick #1
Philadelphia Eagles +3.5
Best odds
-125
Units: 6/10
Additional Pick
Over 49
Best odds
-110
Units: 5/10
Additional Pick
The Eagles Over 21.5
Best odds
-140
Units: 6/10
Your Expert:
+94%
Stefan Scekic

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